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"Inactive" ingredients in oral medications

Reker D, Blum SM, Steiger C, et al. (2019)

Sci Transl Med · PMID 30867323

Abstract

Oral forms of medications contain "inactive" ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactions, underscoring the need to maximize the tolerability and safety of medications and their inactive ingredients.

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